This is an action comedy full of laughter and warmth, which takes place in a lively apartment building in Manhattan, New York.Every morning, when human residents go out to work and school, the pets in the house quietly wake up and start their wonderful day - chatting and gossiping, teasing each other about their embarrassing things, and racking their brains to put on the cutest look just to win more snack rewards. Among these animals of different personalities, the leader is a witty and humorous terrier (voiced by Louis C.K.).He originally lived a comfortable and favored life and considered himself the center of his master's world.However, this balance was broken by a new member named Duke (voiced by Stonestreet) - this sloppy, temperamentless mixed-breed dog suddenly became the owner's favorite, making the terrier feel that his status was in danger and he felt jealous. In order to regain your favor, the two dogs are accidentally involved in an adventure on the streets of New York.On the way, they met the White Rabbit Snowball (voiced by Hart) who looks sweet on the outside but has a shocking secret inside.It turned out that Snowball was the leader of the legion formed by abandoned pets. She was determined to plan to revenge on humans and try to eradicate all pets loyal to her masters. Faced with this sudden crisis, this pair of dog partners who once did not deal with each other must work together to fight wits and courage in the city. They must not only stop Snowball's conspiracy, but also return home before supper and regain the warm belongings that belong to them.